Nanomonitors: Electrical Immunoassays towards Clinical Diagnostics
نویسندگان
چکیده
Proteomics research has elucidated many new biomarkers that have the potential to greatly improve disease diagnosis. Electrical biosensors can be extremely sensitive and can be modified to function as protein detectors, meeting the improved performance parameters requirements. We employ the protein specific capacitance measurement method as the basis for protein biomarker detection. We have demonstrated the performance parameters for individual protein biomarker detection in purified and spiked serum samples to be comparable to ELISA. We have explored the feasibility of concurrent detection of the two protein biomarkers with comparable performance parameters.
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